AUTOPSY

From GuentertWiki
Revision as of 19:28, 18 January 2010 by Guentert (Talk | contribs)
(diff) ← Older revision | Latest revision (diff) | Newer revision → (diff)
Jump to: navigation, search

Automated peak picking in NMR spectroscopy


AUTOPSY is a program for automated peak picking of multidimensional protein NMR spectra. The main elements of this program are a novel function for local noise level calculation, the use of symmetry considerations, and the use of line shapes extracted from well separated peaks for resolving groups of strongly overlapping peaks. The algorithm generates peak lists with chemical shift values and integrals, and a reliability measure for the recognition of each peak.

Availability

  • AUTOPSY is available free-of-charge from the group of Prof. K. Wüthrich at ETH Zürich.
  • AUTOPSY compiled for Linux (Ubuntu 9.10) is available free-of-charge to all academic users who agree with the copyright and legal information.

References

  • Koradi, R., Billeter, M., Engeli, M., Güntert, P. & Wüthrich, K. Automated peak picking and peak integration in macromolecular NMR spectra using AUTOPSY. J. Magn. Reson.135, 288-297 (1998)
Personal tools
Intranet
Create Account